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 Publication List |
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欧文原著 |
| 54. |
Nojima K, Sugimoto K, Ueda H, Babaya N, Ikegami H, Rakugi H. NEW !
Analysis of hepatic gene expression profile in a spontaneous mouse model of type 2 diabetes under a high sucrose diet.
Endocr J. 2012 Nov 6. [Epub ahead of print]. LINK |
| 53. |
Babaya, N., Ueda, H., Noso, S., Hiromine, Y., Nojima, K., Itoi-Babaya, M., Kobayashi, M., Fujisawa, T., Ikegami, H. NEW !
Dose effect and mode of inheritance of diabetogenic gene on mouse chromosome 11.
Experimental Diabetes Research. (In press). |
| 52. |
Ueda H, Morphew MK, McIntosh JR, Davis MM.
CD4+ T-cell synapses involve multiple distinct stages.
Proc Natl Acad Sci U S A. 2011;108(41):17099-104. LINK |
| 51. |
Haseda F, Imagawa A, Murase-Mishiba Y, Sano H, Hirano-Kuwata S, Ueda H, Terasaki J, Hanafusa T.
Low CTLA-4 expression in CD4(+) helper T-cells in patients with fulminant type 1 diabetes.
Immunol Lett. 2011;139(1-2):80-6. |
| 50. |
Babaya N, Fujisawa T, Nojima K, Itoi-Babaya M, Yamaji K, Yamada K, Kobayashi M, Ueda H, Hiromine Y, Noso S, Ikegami H.
Direct evidence for susceptibility genes for type 2 diabetes on mouse chromosomes 11 and 14.
Diabetologia. 53:1362-1371. (2010) |
| 49. |
Itoi-Babaya M, Ikegami H, Fujisawa T, Ueda H, Nojima K, Babaya N, Kobayashi M, Noso S, Kawaguchi Y, Yamaji K, Shibata M, Ogihara T
Fatty liver and obesity: phenotypically correlated but genetically distinct traits in a mouse model of type 2 diabetes.
Diabetologia. 50:1641-1648. (2007) |
| 48. |
Nojima K, Ikegami H, Fujisawa T, Ueda H, Babaya N, Itoi-Babaya M, Yamaji K, Shibata M, Ogihara T
Food hardness as environmental factor in development of type 2 diabetes.
Diabetes Res Clin Pract. 74(1):1-7. (2006) |
| 47. |
Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G, Rainbow DB, Hunter KM, Smith AN, Di Genova G, Herr MH, Dahlman I, Payne F, Smyth D, Lowe C, Twells RC, Howlett S, Healy B, Nutland S, Rance HE, Everett V, Smink LJ, Lam AC, Cordell HJ, Walker NM, Bordin C, Hulme J, Motzo C, Cucca F, Hess JF, Metzker ML, Rogers J, Gregory S, Allahabadia A, Nithiyananthan R, Tuomilehto-Wolf E, Tuomilehto J, Bingley P, Gillespie KM, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Maxwell AP, Carson DJ, Patterson CC, Franklyn JA, Clayton DG, Peterson LB, Wicker LS, Todd JA, Gough SC
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
Nature 423:506-511. (2003) |
| 46. |
Babaya N, Ikegami H, Fujisawa T, Ueda H, Nojima K, Itoi-Babaya M, Yamada K, Fukuda M, Kawaguchi Y, Yamato E, Makino S, Ogihara T
Sequence analysis of Tnf as a candidate for Idd1.
Autoimmunity 35:63-66. (2002) |
| 45. |
Shen GQ, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Yamada K, Babaya N, Ogihara T
Insulin receptor substrate-1 polymorphism in non-insulin-dependent diabetes mellitus and essential hypertension: association study and meta-analysis.
Diabetes Res 35:77-86. (2001) |
| 44. |
Ueda H, Ikegami H, Fujisawa T, Kawaguchi Y, Nojima K, Babaya N, Yamada K, Shibata M, Yamato E, Ogihara T
Mapping and promoter sequencing of HNF-1 beta gene in diabetes-prone and -resistant mice.
Diabetes Res Clin Prac 53:67-71. (2001) |
| 43. |
Babaya N, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Itoi-Babaya M, Taniguchi H, Noso S, Horiki M, Yamada K, Fukuda M, Ogihara T
Lack of association between hepatocyte nuclear factor-1b gene and common forms of type 2 diabetes in the Japanese population.
Diabetes Nutr Metab 14:220-224. (2001) |
| 42. |
Yamada K, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Itoi M, Babaya N, Shibata M, Makino S, Ogihara T
Sequence analysis of candidate genes for common susceptibility to type 1 and type 2 diabetes in mice.
Endocrine J 48:241-247. (2001) |
| 41. |
Hamada Y, Ikegami H, Ueda H, Kawaguchi Y, Yamato E, Nojima K, Yamada K, Babaya N, Shibata M, Ogihara T
Insulin secretion to glucose as well as non-glucose stimuli is impaired in spontaneously diabetic Nagoya-Shibata-Yasuda (NSY) mice.
Metabolism 50:891-894. (2001) |
| 40. |
Johnson GC, Esposito L, Barratt BJ, Smith AN, Heward J, Di Genova G, Ueda H, Cordell HJ, Eaves IA, Dudbridge F, Twells RC, Payne F, Hughes W, Nutland S, Stevens H, Carr P, Tuomilehto-Wolf E, Tuomilehto J, Gough SC, Clayton DG, Todd JA
Haplotype tagging for the identification of common disease genes.
Nat Genet. 29:233-237. (2001) |
| 39. |
Babaya N, Ikegami H, Kawaguchi Y, Fujisawa T, Ueda H, Fukuda M, Makino S, Ogihara T
Congenic mapping and functional analysis of second component of MHC-linked diabetogenic gene (Idd16).
Int J Diabetes 8:1-7. (2000) |
| 38. |
Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Ono M, Nishino M, Taniguchi H, Noso S, Kazunori Y, Babaya N, Ogihara T
Age-related association of MHC class I chain-related gene A (MICA) with type I (insulin-dependent) diabetes mellitus.
Hum Immunol 61:624-629. (2000) |
| 37. |
Ueda H, Ikegami H, Kawaguchi Y, Fujisawa T, Nojima K, Babaya N, Yamada K, Shibata M, Yamato E, Ogihara T
Paternal-maternal effects on phenotypic characteristics in spontaneously diabetic NSY mice.
Metabolism 49:651-659. (2000) |
| 36. |
Ueda H, Ikegami H, Kawaguchi Y, Fujisawa T, Nojima K, Babaya N, Yamada K, Shibata M, Yamato E, Ogihara T
Age-dependent changes in phenotypes and candidate gene analysis in a polygenic animal model of type II diabetes; NSY mouse.
Diabetologia 43:932-938. (2000) |
| 35. |
Fujisawa T, Ikegami H, Tsutsui T, Kawaguchi Y, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Noso S, Yamada K, Babaya N, Ogihara T
Renal tubular function affects glycosuria-related urinary excretion of 1,5-anhydroglucitol.
Diabetes Care 48:863-864. (1999) |
| 34. |
Fujisawa T, Ikegami H, Yamato E, Kawaguchi Y, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino T, Noso S, Yamada K, Babaya N, Okamoto N, Ohguro N, Fukuda M, Ogihara T
Association of plasma fibrinogen level and blood pressure with diabetic retinopathy, and renal complications associated with proliferative diabetic retinopathy, in type 2 diabetes mellitus.
Diabetic Medicine 16:522-526. (1999) |
| 33. |
Ueda H, Ikegami H, Kawaguchi Y, Fujisawa T, Yamato E, Shibata M, Ogihara T
Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait.
Diabetes 48:1168-1174. (1999) |
| 32. |
Shen G-Q, Ikegami H, Kawaguchi Y, Fujisawa T, Hamada Y, Ueda H, Shintani M, Nojima K, Kawabata Y, Babaya N, Fu J, Hotta M, Yamato E, Ogihara T
Association studies on human chromosome 1p22 and insulin-dependent diabetes mellitus.
Diabetes Res 33:107-113. (1998) |
| 31. |
Babaya N, Ikegami H, Kawaguchi Y, Nakagawa Y, Fujisawa T, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Yamada K, Shen G-Q, Fukuda M, Ogihara T
Hepatocyte nuclear factor-1a gene and non-insulin-dependent diabetes mellitus in the Japanese population.
Acta Diabetologica 35:150-153. (1998) |
| 30. |
Shen G-Q, Ikegami H, Kawaguchi Y, Fujisawa T, Hamada Y, Ueda H, Shintani M, Nojima K, Kawabata Y, Yamada K, Babaya N, Ogihara T
Asp905Tyr polymorphism of skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 gene in non-insulin-dependent diabetes mellitus.
Diabetes Care 21:1086-1089. (1998) |
| 29. |
Fu J, Ikegami H, Kawaguchi Y, Fujisawa T, Kawabata Y, Hamada Y, Ueda H, Shintani M, Nojima K, Babaya N, Shen Q-J, Uchigata Y, Urakami T, Omori Y, Shima K, Ogihara T
Association of distal chromosome 2q with IDDM in Japanese subjects.
Diabetologia 41:228-232. (1998) |
| 28. |
Fujisawa T, Ikegami H, Kawaguchi Y, Hamada Y, Ueda H, Shintani M, Fukuda M, Ogihara T
Meta-analysis of the association of Insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy.
Diabetologia 41:47-53. (1998) |
| 27. |
Oga T, Ikegami H, Yamato E, Takekawa K, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Effect of α-glucosidase inhibitor on postprandial hyperglycemia in insulin-treated diabetic patients.
Diabetes Res 32:197-203. (1997) |
| 26. |
Takekawa K, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Shintani M, Ogihara T
Analysis of glucokinase locus as a candidate for shared genetic susceptibility between NIDDM and IDDM.
Diabetes Res 32:11-18. (1997) |
| 25. |
Fujisawa T, Ikegami H, Hashimoto J, Yamato E, Kawaguchi Y, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Babaya N, Fukuda M, Ogihara T
Bone mineral density in a rat model of non-insulin-dependent diabetes mellitus.
Diabetes Nutr Metab 10:180-184. (1997) |
| 24. |
Yamato E, Ikegami H, Kawaguchi Y, Fujisawa T, Hamada Y, Oga T, Ueda H, Shintani M, Ogihara T
A case of insulin-dependent diabetes mellitus associated with autoimmune thyroiditis and rheumatoid arthritis.
Am J Med Sci 313:64-66. (1997) |
| 23. |
Yamato E, Ikegami H, Takekawa K, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Glucose-dependent expression of receptor genes for glucagon and GLP-1 in a mouse pancreatic beta cell line.
Horm Metab Res 29:56-59. (1997) |
| 22. |
Kawaguchi Y, Ikegami H, Shen G-Q, Nakagawa Y, Fujisawa T, Hamada Y, Ueda H, Fu J, Uchigata Y, Kaitagawa Y, Omori Y, Shima K, Ogihara T
Insulin gene region contributes to genetic susceptibility to, but may not to low incidence of, insulin-dependent diabetes mellitus in Japanese.
Biochem Biophys Res Commun 233:283-287. (1997) |
| 21. |
Yamato E, Ikegami H, Takekawa K, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Internal marker for quantitative analysis of mRNA by RT-PCR in pancreatic beta cells.
Diabetologia 39:747-748. (1996) |
| 20. |
Fu J, Ikegami H, Yamato E, Nakagawa Y, Kawaguchi Y, Fujisawa T, Hamada Y, Ueda H, Shen G-Q, Ogihara T
Age- and HLA-dependent heterogeneity in the association of a marker on chromosome 2q with insulin-dependent diabetes mellitus.
Diabetes Res 31:215-222. (1996) |
| 19. |
Hamada Y, Ikegami H, Yamato E, Takekawa K, Fujisawa T, Nakagawa Y, Ueda H, Ogihara T.
Polymorphism of TNFB gene is associated with specific HLA haplotypes, but not with insulin-dependent diabetes mellitus in Japanese.
Diabetes Res 31:171-179. (1996) |
| 18. |
Shintani M, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Miki T, and Ogihara T
A novel microsatellite polymorphism in the human OB gene: a highly polymorphic marker for linkage analysis.
Diabetologia 39:1398-1401. (1996) |
| 17. |
Fujisawa T, Ikegami H, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Oga T, Ueda H, Shintani M, Fukuda M, Ogihara T
Association of Trp64Arg mutation of beta3-adrenergic receptor with NIDDM and body weight gain.
Diabetologia 39:349-352. (1996) |
| 16. |
Hamada Y, Ikegami H, Fujioka Y, Yamato E, Takekawa K, Fujisawa T,Nakagawa Y, Ueda H, Fu J, Shen G-Q, Miki T, Ogihara T
The glycogen synthase gene in NIDDM and hypertension.
Diabetologia 38:1249-1250. (1995) |
| 15. |
Fujisawa T, Ikegami H, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Class I HLA is associated with age-at-onset of IDDM, while class II HLA confers susceptibility to IDDM.
Diabetologia 38:1494-1496. (1995) |
| 14. |
Fu J, Ikegami H, Yamato E, Kawaguchi Y, Takekawa K, Fujisawa T, Nakagawa Y, Hamada Y, Hamada Y, Ueda H, Shen GQ, Ogihara T
Detection of MspI RFLP in human THY1 gene by the polymerase chain reaction.
Jpn J Hum Genet 40:279-280. (1995) |
| 13. |
Fujioka Y, Takekawa K, Nakagawa Y, Hamada Y, Ikegami H, Yamato E, Fujisawa T, Ueda H, Miki T, Ogihara T
Insulin receptor gene polymorphism and hyperinsulinemia in hypertensive patients.
Hypertens Res 18:205-207. (1995) |
| 12. |
Fujisawa T, Ikegami H, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Yoshiiwa A, Miki T, Fukuda M, Ogihara T
Apolipoprotein E gene polymorphism and diabetic microangiopathy in non-insulin-dependent diabetes mellitus.
Diabetes Res 29:57-64. (1995) |
| 11. |
Yamato E, Ikegami H, Takekawa K, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Expression of regulated endocrine-specific protein (RESP) 18 gene in mouse insulinoma cell line and various mouse endocrine tissues.
Diabetes Res 29:13-16. (1995) |
| 10. |
Fujisawa T, Ikegami H, Shen G-Q, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Rakugi H, Higaki J, Ohishi M, Fujii K, Fukuda M, Ogihara T
Angiotensin I-converting enzyme gene polymorphism is associated with myocardial infarction, but not with retinopathy or nephropathy, in non-insulin-dependent diabetes mellitus.
Diabetes Care 18:983-985. (1995) |
| 9. |
Fujisawa T, Ikegami H, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
A mutation in the glucagon receptor gene (Gly40Ser): heterogeneity in the association with diabetes mellitus.
Diabetologia 38:983-985. (1995) |
| 8. |
Nakagawa Y, Ikegami H, Yamato E, Takekawa K, Fujisawa T, Hamada Y, Ueda H, Uchigata Y, Miki T, Kumahara Y, Ogihara T
A new mitochondrial DNA mutation associated with non-insulin-dependent diabetes mellitus.
Biochem Biophys Res Comm 209:664-668. (1995) |
| 7. |
Ueda H, Ikegami H, Yamato E, Fu J, Fukuda M, Shen G-Q, Kawaguchi Y, Takekawa K, Fujioka Y, Fujisawa T, Nakagawa Y, Hamada Y, Shibata M, Ogihara T
The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity.
Diabetologia 38:503-508. (1995) |
| 6. |
Ikegami H, Makino S, Yamato E, Kawaguchi Y, Ueda H, Sakamoto T, Takekawa K, Ogihara T
Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.
J Clin Invest 96:1936-1942. (1995) |
| 5. |
Takekawa K, Ikegami H, Yamato E, Fujioka Y, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Absence of association of adenosine deaminase locus with type 2 (non-insulin-dependent) diabetes mellitus in Japanese population.
Diabetes Res 27:103-109. (1994) |
| 4. |
Takekawa K, Ikegami H, Fukuda M, Ueda H, Kawaguchi Y, Fujioka Y, Fujisawa T, Ogihara T
Early-onset type 2 (non-insulin-dependent) diabetes mellitus is associated with glucokinase locus, but not with adenosine deaminase locus, in Japanese population.
Diabetes Res Clin Prac 23:141-146. (1994) |
| 3. |
Kawaguchi Y, Ikegami H, Fukuda M, Takekawa K, Fujioka Y, Fujisawa T, Ueda H, Ogihara T
No association of TAP and LMP genes with type 1 (insulin-dependent) diabetes mellitus.
Life Sciences 54:2049-2053. (1994) |
| 2. |
Ikegami H, Fukuda M, Kawaguchi Y, Fujioka Y, Ueda H, Ogihara T
A microsatellite polymorphism in the human insulin receptor gene: a highly informative marker for linkage analysis.
Diabetes Res Clin Prac 20:7-10. (1993) |
| 1. |
Ikegami H, Kawaguchi Y, Ueda H, Fukuda M, Takekawa K, Fujioka Y, Fujisawa T, Uchida K, Ogihara T
MHC-linked diabetogenic gene of the NOD mouse: Molecular mapping of the 3' boundary of the diabetogenic region.
Biochem Biophys Res Comm 192:677-682. (1993) |
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欧文総説 |
| 1. |
Sato N, Takeda S, Uchio-Yamada, K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential.
Curr Aging Sci. 2011;4(2):118-27. |
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欧文原著 (Proceedings) |
| 23. |
Ono M, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Nishino M, Taniguchi H, Noso S, Yamada K, Itoi M, Babaya N, Miki T, Ogihara T
Effect of troglitazone, an insulin sensitizer, on liver function in patients with type 2 diabetes mellitus.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp443-446 |
| 22. |
Shintani M, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Nojima K, Kawabata Y, Babaya N, Ono M, Nishino M, Yamada K, Itoi M, Kinashi A, Sakata T, Ogihara T
An interview-based assessment of eating behaviors in diabetic and control subjects.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp375-378 |
| 21. |
Yamada K, Ikegami H, Yoneda H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Itoi M, Taniguchi H, Noso S, Babaya N, Miki T, Ogihara T
Impaired insulin secretion in addition to insulin resistance contributes to the development of overt diabetes in Werner’s syndrome.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp119-122 |
| 20. |
Babaya N, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Itoi M, Taniguchi H, Noso S, Yamada K, Ogihara T
Lack of association between hepatocyte nuclear factor genes and common forms of type 2 diabetes in the Japanese population.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp115-118 |
| 19. |
Nojima K, Ikegami H, Ueda H, Kawaguchi Y, Fujisawa T, Hamada Y, Hotta M, Yamada K, Babaya N, Ogihara T
Effect of environmental factors on phenotypic characteristics of spontaneously diabetic NSY mice.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp111-114 |
| 18. |
Nishino M, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Yamada K, Itoi M, Taniguchi H, Noso S, Babaya N, Fu J, Ogihara T
Association of distal chromosome 2q with type 1 diabetes in Japanese subjects.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp99-102 |
| 17. |
Kawabata Y, Ikegami H, Kawaguchi Y, Hotta M, Ueda H, Shintani M, Nojima K, Ono M, Nishino M, Taniguchi H, Noso S, Yamada K, Itoi M, Babaya N, Ogihara T
Typing of microsatellite markers within HLA region using the primer extension preamplification (PEP) method.
In ”Diabetes Mellitus: Recent Advances for the 21st Century”, Shichiri M, Shinn SH, Hotta N eds, Elsevier Science B.V., Amsterdam, 2000; pp95-98 |
| 16. |
Kawabata Y, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Babaya N, Fu J, Shen G-Q, Ogihara T
The effect of PGE1 on symptom and vascular cell damage in diabetic patients with limb numbness.
In "Recent Advances on the Pathogenesis and Management of Diabetes Mellitus", Shinn SH, Shichiri M, Kim K-W eds, Elsevier Science, Singapore, 1998; pp400-404 |
| 15. |
Hamada Y, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Babaya N, Fu J, Shen G-Q, Ogihara T
Analysis of beta cell function in spontaneous diabetic NSY mice.
In "Recent Advances on the Pathogenesis and Management of Diabetes Mellitus", Shinn SH, Shichiri M, Kim K-W eds, Elsevier Science, Singapore, 1998; pp118-122 |
| 14. |
Nojima K, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Hamada Y, Hotta M, Ueda H, Shintani M, Kawabata Y, Babaya N, Fu J, Shen G-Q, Ogihara T
Characteristics of NIDDM patients with fasting hyperglycemia.
In "Recent Advances on the Pathogenesis and Management of Diabetes Mellitus", Shinn SH, Shichiri M, Kim K-W eds, Elsevier Science, Singapore, 1998; pp142-146 |
| 13. |
Babaya N, Ikegami H, Fujisawa T, Yamato E, Kawaguchi Y, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Fu J, Shen G-Q, Ogihara T
Absence of a Gly40Ser mutation in the glucagon receptor genes of Japanese NIDDM and hypertension patients.
In "Recent Advances on the Pathogenesis and Management of Diabetes Mellitus", Shinn SH, Shichiri M, Kim K-W eds, Elsevier Science, Singapore, 1997; pp118-122 |
| 12. |
Shintani M, Ikegami H, Yamato E, Kawaguchi Y, Fujisawa T, Hamada Y, Hotta M, Ueda H, Nojima K, Kawabata Y, Babaya N, Shen G-Q, Kinashi A, Sakata T, Ogihara T
An interview-based assessment of eating behavior in nonobese and obese subjects.
In "Recent Advances on the Pathogenesis and Management of Diabetes Mellitus", Shinn SH, Shichiri M, Kim K-W eds, Elsevier Science, Singapore, 1997; pp87-90 |
| 11. |
Fujisawa T, Ikegami H, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Ogihara T
Effect of aging, renal function and renal tubular function on urinary excretion of 1,5-anhydroglucitol.
In "Diabetes mellitus: New aspects of pathogenesis and treatment", Kaneko T, Huh KB, Shichiri M, Oka Y eds, Nishimura / Smith Gordon, UK, 1997; pp295-296 |
| 10. |
Yamato E, Ikegami H, Takekawa K, Fujisawa T, Nakagawa Y, Hamada Y, Ueda H, Cha T, Ogihara T
Effects of glucagon, somatostatin and epinephrine on insulin release from a pancreatic beta cell line, MIN6.
In "Diabetes mellitus: New aspects of pathogenesis and treatment", Kaneko T, Huh KB, Shichiri M, Oka Y eds, Nishimura / Smith Gordon, UK, 1997; pp151-153 |
| 9. |
Ueda H, Ikegami H, Yamato E, Fu J, Fukuda M, Shen G, Hamada Y, Kawaguchi Y, Takekawa K, Fujisawa T, Nakagawa Y, Shibata M, Ogihara T
The NSY mouse: an animal model of spontaneous NIDDM and fatty liver.
In "Diabetes mellitus: New aspects of pathogenesis and treatment", Kaneko T, Huh KB, Shichiri M, Oka Y eds, Nishimura / Smith Gordon, UK, 1997; pp107-109 |
| 8. |
Hamada Y, Ikegami H, Yamato E, Takekawa K, Fujisawa T, Nakagawa Y, Ueda H, Ogihara T
Polymorphism of TNFB gene and non-insulin-dependent diabetes mellitus (NIDDM).
In "Diabetes mellitus: New aspects of pathogenesis and treatment", Kaneko T, Huh KB, Shichiri M, Oka Y eds, Nishimura / Smith Gordon, UK, 1997; pp95-97 |
| 7. |
Takekawa K, Ikegami H, Yamato E, Fujisawa T, Nakagawa Y, Hamada Y, Oga T, Ueda H, Shintani M, Ogihara T
Search for a common genetic susceptibility of IDDM and NIDDM.
In "Diabetes mellitus: New aspects of pathogenesis and treatment", Kaneko T, Huh KB, Shichiri M, Oka Y eds, Nishimura / Smith Gordon, UK, 1997; pp93-94 |
| 6. |
Nakagawa Y, Ikegami H, Kawaguchi Y, Takekawa K, Fujioka Y, Fujisawa T, Hamada Y, Ueda H, Ogihara T
Clinical and genetic analysis of mitochondrial DNA mutation in patients with diabetes mellitus.
In "Pathogenesis and Treatment of NIDDM and its related protein" Sakamoto N, Alberti KGMM, Hotta N. Elsevier Science B.V., 1994; pp163-166 |
| 5. |
Fu J, Ikegami H, Ueda H, Fukuda M, Yamato E, Kawaguchi Y, Takekawa K, Fujioka Y, Fujisawa T, Nakagawa Y, Hamada Y, Shibata M, Ogihara T
Endocrinological and histological analysis of glucose intolerance in NSY mice: a longitudinal study.
In "Current Status of Diabetes Mellitus in East Asia" Mimura G, Quian R-L, Murakami K eds, Elsevier Science B.V.,
1994; pp197-200 |
| 4. |
Takekawa K, Ikegami H, Fukuda M, Kawaguchi Y, Fujioka Y, Fujisawa T, Ueda H, Kinashi A, Ogihara T
Characteristics of diabetes mellitus in elderly urban residents.
In "Insulin resistance in human disease", Huh KB et al. Eds, Elsevier Science Publishers B.V., Amsterdam,
1993, pp65-68 |
| 3. |
Fujioka Y, Ikegami H, Fukuda M, Kawaguchi Y, Takekawa K, Fujisawa T, Ueda H, Ogihara T
Genetic factors associated with insulin resistance in hypertensive patients.
In "Insulin resistance in human disease", Huh KB et al. Eds, Elsevier Science Publishers B.V., Amsterdam,
1993, pp187-190 |
| 2. |
Ueda H, Ikegami H, Fukuda M, Kawaguchi Y, Takekawa K, Fujioka Y, Fujisawa T, M Shibata, Ogihara T
Longitudinal studies of glucose intolerance spontaneously diabetic NSY mice.
In "Insulin resistance in human disease", Huh KB et al. Eds, Elsevier Science Publishers B.V., Amsterdam,
1993, pp213-216 |
| 1. |
Kawaguchi Y, Ikegami H, Fukuda M, Takekawa K, Fujioka Y, Fujisawa T, Ueda H, Ogihara T
Analysis of insulin gene region in Japanese IDDM patients.
In "Insulin resistance in human disease", Huh KB et al. Eds, Elsevier Science Publishers B.V., Amsterdam,
1993, pp175-178 |
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欧文著書 |
| 1. |
Ueda H, Ikegami H, Shibata M, Ogihara T
The NSY mouse: an animal model of human type 2 diabetes mellitus with polygenic inheritance.
In: Animal Models of Diabetes A Primer. Sima AAF and Shafrir E (eds.), Harwood Academic Publishers, Amsterdam, pp43-61. (2000) |
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邦文総説 |
| 7. |
上田裕紀
「1型糖尿病の発症機構ー最新の知見ー」
内分泌・糖尿病・代謝内科, 32(6):530-538, (2011) |
| 6. |
上田裕紀，池上博司、荻原俊男
「広範囲血液・尿化学検査、免疫学的検査：モチリン」
日本臨床 57（1999年増刊号）:345-348. (1999) |
| 5. |
柴田昌雄、池上博司、上田裕紀
「NSYマウス」
Diabetes Frontier 9:465-69. (1998) |
| 4. |
上田裕紀、池上博司、荻原俊男
「インスリン抵抗性症候群の管理 - インスリン感受性改善薬 」
血圧 4:739-742. (1996) |
| 3. |
上田裕紀，池上博司，荻原俊男
「モチリン」
日本臨床 1995 増刊号 「広範囲血液・尿化学検査（中巻）ーその数値をどう読むかー」 53:640-643. (1995) |
| 2. |
上田裕紀，池上博司，荻原俊男
「マイクロサテライトマーカー」
BIOclinica 9:60-62. (1994) |
| 1. |
上田裕紀，池上博司，島健二
「加齢と耐糖能：糖尿病診断のピットホール」
Practice 9:404-408. (1992) |
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邦文著書 |
| 3. |
上田裕紀
「T細胞の制御からみた1型糖尿病の発症機構」
「分子糖尿病学の進歩―基礎から臨床までー」金原出版、66-73, (2009) |
| 2. |
上田裕紀，池上博司、荻原俊男
「インスリン感受性増強薬」
「KEY WORD 1999-2000 高血圧」 先端医学社、p40-41. (1999) |
| 1. |
上田裕紀，池上博司，荻原俊男
「NSYマウス」
「糖尿病研究ストラテジー」 秀潤社、 p390-391. (1995) |
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|
|
 Seminar / Symposium / Invited |
|
セミナー・シンポジウム・招待講演・業績発表会 |
| 15. |
【2011/07/07】
「第1回大阪内分泌代謝カンファレンス」
案内（pdf）
|
| 14. |
【2011/02/05】
第4回神戸生活習慣病研究会
内容 (pdf) |
| 13. |
【2010/09/28】
「第56回未来医療セミナー」
ポスター（pdf） 未来医療センターHP
|
| 12. |
【2010/03/26】
「大阪大学生命科学若手研究アプレンティスプログラム」医学系研究科 平成21年度業績発表会」
プログラム内容 (pdf) |
| 11. |
【2010/01/22】
第24回日本糖尿病・肥満動物学会年次学術集会
「自然発症2型糖尿病モデルＮＳＹマウスを用いた多因子疾患の機能分割」
プログラム内容 (pdf) |
| 10. |
【2009/11/05】
第4回生活習慣病と動脈硬化のUp to date
「炎症制御システム〜免疫シナプス〜の構造と動態」
ポスター(pdf) |
| 9. |
【2009/10/09】
「大阪大学生命科学若手研究アプレンティスプログラム」第二回シンポジウム」
「免疫シナプス不全へのアプローチ」
ポスター(pdf) |
| 8. |
【2009/04/16】
第10回 ＫＫ21抗老化・高血圧研究会
−日本高血圧学会生涯教育講演会−
「免疫シナプス不全へのアプローチ」
ポスター(pdf) |
| 7. |
【2009/02/24】
「大阪大学生命科学若手研究アプレンティスプログラム」第一回シンポジウム」
「T lymphocyte signaling and diabetogenic genes」
ポスター(pdf) |
| 6. |
【2009/01/10】
第10回Victor J. Dzau,研究会
「免疫シナプス不全へのアプローチ」
プログラム(doc) |
| 5. |
【2008】
第51回日本糖尿病学会年次学術集会、東京国際フォーラム 会長 東京大学大学院医学系研究科 糖尿病・代謝内科 門脇 孝 シンポジウム6 ：1型糖尿病の発症機構
“免疫シナプスの細胞内微細構造とその動態の解析 −T細胞の内側から見たI型糖尿病−”
|
| 4. |
【2005】
International Symposium Molecular Diabetology and Endocrinology, September 22-24, Ulm, Germany Host: Professor Bernard O. Bohem, Ulm University
“Four dimensional analysis of the immunological synapse by EM tomography”
|
| 3. |
【2002】
Special seminar in Department of Microbiology and Immunology, January, Stanford University, USA Host: Professor Mark M. Davis, Stanford University
“Novel human autoimmune susceptibility-T cell regulatory gene/ CTLA4”
|
| 2. |
【2002】
Novel human autoimmune susceptibility -T cell regulatory gene/CTLA4.
Wellcome Trust International Fellows Meeting, January 21, The Royal College of Physicians, London, UK (oral presentation).
|
| 1. |
【200１】
Association of the CTLA4 gene with Graves' disease, Type 1 Diabetes and Hashimoto's Thyroiditis.
Wellcome Trust International Fellows Meeting, January, Cambridge, UK (poster).
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| |
|
English presentations |
| |
1992:
Ueda H et al.: A case with hyperinsulinemia due to hypersecretion of glucagon like peptide (GLP)-1.
The 52nd Annual Meeting of the American Diabetes Association, June 20-23, San Antonio, Texas, USA (poster)
1993:
Ueda H et al.: Pathogenesis of glucose intolerance in spontaneously diabetic NSY mice.
The Seventh Korea-Japan Symposium on Diabetes Mellitus, April 13-14, Seoul, Korea (oral presentation)
1994:
Ueda H et al.: Longitudinal studies of glucose intolerance spontaneously diabetic NSY mice.
Lessons from Animal Diabetes: International Workshop IV, November, Omiya, Saitama, Japan (poster)
1995:
Ueda H et al.: The NSY mouse: an animal model of spontaneous NIDDM and fatty liver.
The eighth Japan Korea Symposium on Diabetes Mellitus, Ube, Japan (oral presentation)
1997:
Ueda H et al.: Mode of Inheritance of Diabetes Mellitus and Diabetes-related Phenotypes in Spontaneously Diabetic NSY mice.
The 16th International Diabetes Federation Congress, July, 20-25, Helsinki, Finland (poster)
Ueda H et al.: Mode of Inheritance of Diabetes Mellitus and Diabetes-related Phenotypes in Spontaneously Diabetic NSY mice.
Genetics of Diabetes satellite meeting of the 16th IDF Congress, July 25-27, Ystad, Sweden (poster)
1998:
Ueda H et al.: Autosomal Dominant Mode of Inheritance of Diabetes Mellitus in spontaneously diabetic Nagoya-Shibata-Yasuda mice.
The 12th International mouse genome conference, September 30-October 3, Garmisch-Partenkirchen, Germany (poster)
1999:
Ueda H. et al.: Genetic Analysis of Late-onset Type 2 Diabetes in Spontaneously Diabetic NSY mice.
The 59th Annual Meeting of the American Diabetes Association, June 19-22, San Diego, CA, USA (poster)
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| |
 Awards / Evaluation |
|
受賞・評価 |
| 8. |
【平成24年】 NEW !
武田科学振興財団 ビジョナリーリサーチ助成 「リンパ球制御ブレイクスル―の探索」 |
| 7. |
【平成23-25年】 NEW !
日本学術振興会 科学研究費助成事業 基盤研究（Ｂ） 「糖尿病とアルツハイマー病 の相互病態修飾におけるインスリン・シグナルの役割」（代表 里 直行）（研究分担）
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| 6. |
【平成22年】
文部科学省平成22年度科学研究費補助金（研究活動スタート支援）[継続] 「糖尿病遺伝子座・分子の解析」
|
| 5. |
【平成21年】
文部科学省平成21年度科学研究費補助金（若手研究（スタートアップ））[新規] 「糖尿病遺伝子座・分子の解析」
|
| 4. |
【平成16年】
上原記念生命科学財団 「海外留学助成リサーチフェローシップ」
|
| 3. |
【平成14年】
Wellcome Trust International Fellowship Renewal Extension (英国)
|
| 2. |
【平成12年】
Wellcome Trust International Fellowship (英国)
|
| 1. |
【平成11年】
住友生命社会福祉事業団 「海外医学研究助成金」
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| |
 Patents / Other |
|
特許・その他 |
| 2. |
Hisanaga-Oishi Y & Ueda H NEW !
Expressional Regulation of Type 1 Diabetes Susceptibility Genes by TGF-beta in CD4+ T lymphocytes.
Diabetes 61;Supple. (1):A667. (2012) |
| 1. |
「DISEASE ASSOCIATED POLYMORPHISM IN THE CTLA-4 LOCUS」
European Patent EP1392858
Publication Number:WO/2002/074989 |
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